Publications

Cheong K, Jara JS, Sewall LM, Dikiy S, Le X, Wolman N, Ward AB, Wiseman R, Mendoza A. Maternal antiviral history synergizes with pregnancy and lactation to transfer intergenerational systemic immunity through IgG in milk. Biorxiv 2026.08.14.744935 [Preprint]. 2026 August. doi: https://doi.org/10.64898/2026.08.14.744935.

Mehmood A, Basso T, Weiss A, Dikiy S, Fam K, Marinelli D, Manenti S, Wolman N, Zhang M, Briney B, Hang H, Mendoza A. T-bet Expressing B cells are Key Determinants of Protective Immunity Against Norovirus Infection. [Preprint]. 2026 April. doi: 10.64898/2026.03.30.715451.

Mendoza A, Bou-Puerto R, Jara JS, Dikiy S, Giovanelli P, Correa D, Manenti S, Andretta ES, Dahia CL, Rudensky AY. Enkephalin-producing regulatory T cells in the skin restrain local inflammation through control of nociception. Sci Immunol. 2025 Sep 5;10(111):eadz6869. doi: 10.1126/sciimmunol.adz6869. Epub 2025 Sep 5. PubMed PMID: 40911697; PubMed Central PMCID: PMC12478536.

Liu S, Saraiva M, Bartman CR, Saurat N, Rosato PC, Licona-Limon P, Mendoza A, Guthmiller J, Mlynarczyk C, Goldberg E. Women in STEM becoming independent: People should feel free to be themselves and do great science. J Exp Med. 2025 Sep 1;222(9). doi: 10.1084/jem.20251386. Epub 2025 Aug 8. PubMed PMID: 40778912.

Sun J, Lee K, Kutseikin S, Guerrero A, Rius B, Madhavan A, Buasakdi C, Cheong KN, Chatterjee P, Rosen DA, Yoon L, Ardejani MS, Mendoza A, Rosarda JD, Saez E, Kelly JW, Wiseman RL. Identification of a Selective Pharmacologic IRE1/XBP1s Activator with Enhanced Tissue Exposure. ACS Chem Biol. 2025 May 16;20(5):993-1003. doi: 10.1021/acschembio.4c00867. Epub 2025 Apr 15. PubMed PMID: 40231944; PubMed Central PMCID: PMC12523807.

Glasner A, Rose SA, Sharma R, Gudjonson H, Chu T, Green JA, Rampersaud S, Valdez IK, Andretta ES, Dhillon BS, Schizas M, Dikiy S, Mendoza A, Hu W, Wang ZM, Chaudhary O, Xu T, Mazutis L, Rizzuto G, Quintanal-Villalonga A, Manoj P, de Stanchina E, Rudin CM, Pe'er D, Rudensky AY. Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies. Nat Immunol. 2023 May 1;. doi: 10.1038/s41590-023-01504-2. [Epub ahead of print] PubMed PMID: 37127830.

Yewdell WT, Smolkin RM, Belcheva KT, Mendoza A, Michaels AJ, Cols M, Angeletti D, Yewdell JW, Chaudhuri J. Temporal dynamics of persistent germinal centers and memory B cell differentiation following respiratory virus infection. Cell Rep. 2021 Nov 9;37(6):109961. doi: 10.1016/j.celrep.2021.109961. PubMed PMID: 34758310; PubMed Central PMCID: PMC7612942.

Mendoza A, Yewdell WT, Hoyos B, Schizas M, Bou-Puerto R, Michaels AJ, Brown CC, Chaudhuri J, Rudensky AY. Assembly of a spatial circuit of T-bet-expressing T and B lymphocytes is required for antiviral humoral immunity. Sci Immunol. 2021 Jun 11;6(60). doi: 10.1126/sciimmunol.abi4710. PubMed PMID: 34117110; PubMed Central PMCID: PMC8418793.

Brown CC, Gudjonson H, Pritykin Y, Deep D, Lavallée VP, Mendoza A, Fromme R, Mazutis L, Ariyan C, Leslie C, Pe'er D, Rudensky AY. Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity. Cell. 2019 Oct 31;179(4):846-863.e24. doi: 10.1016/j.cell.2019.09.035. Epub 2019 Oct 24. PubMed PMID: 31668803; PubMed Central PMCID: PMC6838684.

Fan X, Moltedo B, Mendoza A, Davydov AN, Faire MB, Mazutis L, Sharma R, Pe'er D, Chudakov DM, Rudensky AY. CD49b defines functionally mature Treg cells that survey skin and vascular tissues. J Exp Med. 2018 Nov 5;215(11):2796-2814. doi: 10.1084/jem.20181442. Epub 2018 Oct 24. PubMed PMID: 30355617; PubMed Central PMCID: PMC6219731.

Levine AG, Mendoza A, Hemmers S, Moltedo B, Niec RE, Schizas M, Hoyos BE, Putintseva EV, Chaudhry A, Dikiy S, Fujisawa S, Chudakov DM, Treuting PM, Rudensky AY. Stability and function of regulatory T cells expressing the transcription factor T-bet. Nature. 2017 Jun 15;546(7658):421-425. doi: 10.1038/nature22360. Epub 2017 Jun 7. PubMed PMID: 28607488; PubMed Central PMCID: PMC5482236.

Mendoza A, Fang V, Chen C, Serasinghe M, Verma A, Muller J, Chaluvadi VS, Dustin ML, Hla T, Elemento O, Chipuk JE, Schwab SR. Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells. Nature. 2017 Jun 1;546(7656):158-161. doi: 10.1038/nature22352. Epub 2017 May 24. PubMed PMID: 28538737; PubMed Central PMCID: PMC5683179.

Fang V, Chaluvadi VS, Ramos-Perez WD, Mendoza A, Baeyens A, Rivera R, Chun J, Cammer M, Schwab SR. Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-γ response. Nat Immunol. 2017 Jan;18(1):15-25. doi: 10.1038/ni.3619. Epub 2016 Nov 14. PubMed PMID: 27841869; PubMed Central PMCID: PMC5675020.

Mendoza A, Bréart B, Ramos-Perez WD, Pitt LA, Gobert M, Sunkara M, Lafaille JJ, Morris AJ, Schwab SR. The transporter Spns2 is required for secretion of lymph but not plasma sphingosine-1-phosphate. Cell Rep. 2012 Nov 29;2(5):1104-10. doi: 10.1016/j.celrep.2012.09.021. Epub 2012 Oct 25. PubMed PMID: 23103166; PubMed Central PMCID: PMC3616498.

Bréart B, Ramos-Perez WD, Mendoza A, Salous AK, Gobert M, Huang Y, Adams RH, Lafaille JJ, Escalante-Alcalde D, Morris AJ, Schwab SR. Lipid phosphate phosphatase 3 enables efficient thymic egress. J Exp Med. 2011 Jun 6;208(6):1267-78. doi: 10.1084/jem.20102551. Epub 2011 May 16. PubMed PMID: 21576386; PubMed Central PMCID: PMC3173249.